Department Lecture Series
Tuesday February 5, 9:45
am, Smith 331
Automated
Oligosaccharide Synthesis and Vaccines
An understanding of immune responses to carbohydrates is vital
for rational vaccine design, but is currently limited in
part because well-defined saccharide structures are difficult
to access. This talk will discuss automated fluorous-phase
carbohydrate synthesis as an alternative to solid-phase
approaches for the rapid synthesis of oligosaccharides and how
this fluorous-tagging strategy also facilitates methods for
directly
screening these synthetic
carbohydrates for their biological activities.
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