Nicola L. Pohl
Iowa State University


Nicola L. Pohl, Associate Professor and Caldwell Chair of Chemistry, received her B.A. degree from Harvard College in 1991 and her Ph.D. in chemistry from the University of Wisconsin-Madison in 1997. Following an NIH Postdoctoral Fellowship in the Department of Chemical Engineering at Stanford University she joined the faculty at Iowa State University in the fall of 2000 to study protein biocatalysts, synthetic methods, and carbohydrates. She is a member of the Department of Chemistry and the Plant Sciences Institute and was named a Cottrell Scholar of Research Corporation in 2003. Professor Pohl is the recipient of a National Science Foundation CAREER award in 2004 and was named an Alfred P. Sloan Research Fellow in 2005. She also serves on the Editorial Advisory Board of Carbohydrate Research.

http://www.chem.iastate.edu/faculty/Nicola_Pohl/

Department Lecture Series
Tuesday February 5,
9:45 am, Smith 331

Automated Oligosaccharide Synthesis and Vaccines


An understanding of immune responses to carbohydrates is vital for rational vaccine design, but is currently limited in part because well-defined saccharide structures are difficult to access. This talk will discuss automated fluorous-phase carbohydrate synthesis as an alternative to solid-phase approaches for the rapid synthesis of oligosaccharides and how this fluorous-tagging strategy also facilitates methods for directly screening these synthetic carbohydrates for their biological activities.