University of Minnesota
University of Minnesota

Go to chemistry home page.


Hoye and his researchers discover new chemical reaction

Information about a new chemical reaction discovered by Professor Thomas Hoye and members of his research group, including postdoctorate Beeraiah Baire, and graduate students Dawen Niu, Patrick Willoughby, and Brian Woods, has been published in Nature.

Discovering a new reaction is rare. This chemical reaction, called the hexadehydro-Diels-Alder (HDDA) reaction, is a variant of the classic Diels-Alder reaction, which is published in all chemistry textbooks and taught to all organic chemistry students, that no one has seen or thought of before.

The HDDA reaction is an efficient way of constructing high-energy benzynes. Benzynes are highly valued because of their remarkable efficiency and ability to react with other chemical substances. They are used to build structurally complex benzenoid products, which are stable, versatile, synthetic organic compounds used in the development of pharmaceuticals, including most marketed drugs, agrochemicals, dyes, and polymers.

You can read about the hexadehydro-Diels-Alder reaction online at Nature. This reaction also was highlighted in Chemistry World

The hexadehydro-Diels-Alder reaction forms an aryne from an alkyne and diyne.