The focus of the Veglia Research Group is to
study the structure, function and interactions of membrane proteins
using solution
NMR and solid-state
NMR. Solution NMR studies of membrane proteins in detergent micelles
allow the determination of high resolution structural and dynamics information,
while solid-state NMR is used to obtain structural, dynamic, and orientational
information about membrane proteins in a lipid membrane environment.
We use both methods to study the functional interactions of membrane
protein complexes. We develop computational methods to analyze our experimental
results and use molecular dynamics simulations to support and enhance
our results. Undergraduate and graduate students acquire a multidisciplinary
background through the application of a broad range of biophysical and
biochemical techniques. In addition, they interact with experimental
groups in the areas of Physical Chemistry, Biochemistry, and Chemical
Biology.