Research Interests:

Using solution-state NMR techniques and site-directed mutagenesis to study the correlation between dynamics and function involved in the interactions between the membrane proteins phospholamban and Ca 2+-ATPase.

Education:

2007-present	Ph.D. Student, University of Minnesota Twin Cities Dr. Gianluigi Veglia, Advisor
2004-2007	M.S. Chemistry, University of Minnesota Twin Cities Dr. Gianluigi Veglia, Advisor
2000-2004	B.A. Chemistry, University of Minnesota Twin Cities

Research Positions:

2004-present	Graduate Research Assistant University of Minnesota Twin Cities Department of Chemistry Department of Biochemistry, Molecular Biology, and Biophysics
2003-2004	Undergraduate Research Assistant University of Minnesota Department of Chemistry
2002-2003	Undergraduate Research Assistant University of Minnesota Department of Neuroscience

Teaching Positions:

Fall 2005	Head Teaching Assistant Chem 4511: Advanced Physical Chemistry Laboratory
Spring 2004	Teaching Assistant Chem 5412/8412: Enzyme Mechanisms
2004-2005	Teaching Assistant Chem 1022: General Chemistry II Laboratory

Awards:

2000-2004	U2000 Scholarship
Summer 2003	Multicultural Summer Research Opportunity Program Fellowship
2003-2004	Undergraduate Research Opportunity Fellowship
Spring 2004	American Chemical Society Undergraduate Research Travel Grant

 

Publications:

Traaseth, N.J., Ha, K.N., Verardi, R., Shi, L., Buffy, J.J, Masterson, L.R., Veglia, G., Structural and Dynamic Basis of Phospholamban and Sarcolipin Inhibition of Ca(2+)-ATPase, Biochemistry, 2008, 47, 1, 3-13.

Ha, K.N., Traaseth, N.J., Verardi, R., Zamoon, J., Cembran, A., Karim, C.B., Thomas, D.D., Veglia, G., Controlling the Inhibition of the Sarcoplasmic Ca2+-ATPase by Tuning Phospholamban Structural Dynamics,J. Biol. Chem., 2007, 282, 51, 37205-14.

 

Posters:

Tuning Dynamics to Control Function: NMR Studies of Phospholamban Mutants Ha, K., Traaseth, NJ., Verardi, R., Veglia, G. Frontiers of NMR in Molecular Biology X, Keystone Symposium, Snowbird, UT, January 6 to 11, 2007.

Functional NMR Studies of the Structural Dynamics of Mutants of the Membrane Protein Phospholamban Ha KN., Traaseth, NJ., Zamoon, J., Veglia, G., Frontiers in Structural Biology, Keystone Symposium, Keystone, CO, January 29 to February 3, 2006

Expression, Purification, and Structural Studies of Phospholamban Mutants Ha KN., Zamoon, J., Veglia, G., 227th ACS National Meeting, Anaheim, CA, March 27 to April 1, 2004.

Expression, Purification, and Phosphorylation of Phospholamban Ha KN., Metcalfe, EE., Veglia, G., MSROP Summer Research Symposium, Minneapolis, MN, July 28 2003.