Lei Shi


Graduate Student

Department of Chemistry
207 Pleasant St SE
Minneapolis , MN 55455

 

 

(612) 625-0786

shixx036@umn.edu

 


Research Interests:

My research objective is to develop computational methods for solving the structures and topologies of membrane proteins by solid-state NMR.

Education:


2005-present

Ph.D. Student, University of Minnesota Twin Cities
Dr. Gianluigi Veglia, Dr. Jiali Gao, Advisors

2001-2005

B.S. Physical Chemistry, University of Science and Technology of China (USTC)

Research Positions:


2005-present

Graduate Research Assistant
University of Minnesota Twin Cities
Department of Chemistry

2005

Research Assistant
Department of Inorganic Chemistry, University of Science and Technology of China

2005

Summer Research Program in SOFC (Solid-Oxide fuel cell)

2004

Dalian Institute of Chemical Physics (DICP)

Teaching Positions:


2005-2006

Teaching Assitant
Chem 2311: Organic Chemistry, University of Minnesota

2005

Chemistry Tutor
Organic Chemistry, University of Minnesota

Awards:


2004

Outstanding Undergraduate Research Program

2003-2004

Outstanding Student Scholarship

2002-2003

China Goodwill & Peace Development Foundation Panasonic Electronics Talent Cultivation Foundation Scholarship

2001-2002

Outstanding Student Scholarship

 

Publications:

Porcelli, F., Verardi, R., Shi, L., Henzler-Wildman, K.A., Ramamoorthy, A., Veglia, G., NMR Structure of the Cathelicidin-derived Human Antimicrobial Peptide LL37 in Dodecylphosphocholine Micelles, Biochemistry, 2008, 47, 20, 5565-72.

Traaseth, N.J., Ha, K.N., Verardi, R., Shi, L., Buffy, J.J, Masterson, L.R., Veglia, G., Structural and Dynamic Basis of Phospholamban and Sarcolipin Inhibition of Ca(2+)-ATPase, Biochemistry, 2008, 47, 1, 3-13.

 

Posters:

Solid-State NMR Determination of the Structure and Ca-ATPase Interaction of Sarcolipin. Buffy JJ, Traaseth NJ, Shi L, Thomas DD, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Daytona Beach, Fl, April 22-27, 2007.

Structures of Monomeric and Pentameric Membrane Protein Phospholamban Using Hybrid Solution and Solid-State NMR Structural Constraints. Traaseth NJ, Shi L, Verardi R, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Daytona Beach, Fl, April 22-27, 2007.

Structural Dynamics of Sarcolipin in Lipid Bilayers by Moleuclar Dynamics Simulations and Solid-State NMR; Shi L, Cembran A, Gao J, Veglia G; Biophysical Society Meeting, Baltimore, MD, March 3-7, 2007.

Backbone Assignment, Lipid Topology & Ca-ATPase Interaction of Sarcolipin Revealed by Solid-State NMR. Buffy JJ, Traaseth NJ, Shi L, Thomas DD, Veglia G; Keystone Symposia, Snowbird, Utah, January 6-11, 2007