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Welcome to the website of the Pomerantz Lab at UMN!

The Pomerantz lab is a chemical biology group at the University of Minnesota. Our interdisciplinary research encompasses a wide range of topics including organic synthesis, bioanalytical chemistry, biochemistry and molecular biology for studying the function of transcription factors involved in disease. Our primary goal is to discover small molecules which we can synthesize in the laboratory to modulate the function of transcription factor-proteins interactions, with the ultimate goal of developing new chemical probes for understanding the biology of these proteins.

Lab News

  • Jan 6th-14th 2015 - The 2nd installment of the Chemical Biology bootcamp has started! Eight students from four different research labs particpated in a 6 day chemical biology laboratory series. Special thanks to TA's Andrew Urick, Dr. Laura Hawk, Clifford Gee, and Steve Kirberger for their helpful assistance

  • Jan 5th, 2015 - The Pomerantz Lab is very grateful to the Garber family and relatives for their generous support of our research.

  • December 15th, 2014 - 3rd year graduate student Clifford Gee and undergraduate student Ed Koleski's PrOF NMR screening paper is accepted to Angewandte Chemie.

  • December 8th, 2014 - The Pomerantz lab welcomes Jenna Fernandez as a new rotation student from the Department of Medicinal Chemistry

  • November 21st, 2014 - The Pomerantz lab welcomes Peter Ycas, a new first year chemistry graduate student, to the lab.

  • October 7th, 2014 - 3rd year gaduate student Andrew Urick and postdoctoral associate Dr. Neeraj Mishra publish their paper on PrOF NMR for bromodomains. (DOI: 10.1021/cb5007344).

  • September 15, 2014 - The Pomerantz lab welcomes Dr. Laura Hawk as a new postdoctoral associate.

  • September 8, 2014 - The Pomerantz lab welcomes Evan Alexander as a new rotation student from the Department of Medicinal Chemistry

  • Fall 2014 - The Pomerantz lab welcomes new undergraduate students Makenna Habegger who will be working with graduate student Brie Perell on stabilized peptides and Ed Koleski who will be working with graduate student Clifford Gee on developing small molecule ligands for the KIX protein.

  • Summer 2014 - Prof. Pomerantz receives the NSF CAREER grant, 3rd year student Andrew Urick is appointed as a trainee under an NIH Biotechnology training grant, 3rd year student Clifford Gee is appointed as a trainee under the NIH Chemical Biology Interface Training grant.

  • Spring 2014 - Congratulations to second year students, Andrew Urick, Brie Perell, and Clifford Gee for passing qualifying exams and obtaining Ph.D. candidate status!

  • January 27th, 2014 - Pomerantz lab runs the first Chemical Biology Boot Camp, providing new students with the opportunity to learn basic chemical biology lab skills.

  • June 22nd, 2013 - The Pomerantz Lab and the Haynes lab participate in a summer outreach event at the West 7th Community Center and demo their new fingerprint detection and DNA isolation experiments as part of the Haynes lab "solar cell heist mystery"

  • June 19th, 2013 - The Pomerantz lab runs the first Chemical Biology short course with the Osher Life Long Learning Institute. Great work, Andrew, Drew, and Brie!

  • June 13th, Pomerantz Lab receives an American Cancer Society IRG grant

  • Newest Acquisition; TCI CRYO Prodigy Probe (19F S/N; 2100:1)