Distefano Group Theses

Mathews, B. K. Preparation and evaluation of isoprenoid diphosphate analogs that incorporate azide functional groups: tools for understanding the anticancer properties of farnesyltransferase inhibitors. B.S. Summa Cum Laude, University of Minnesota, Minneapolis, 2004.

Tann, C.-M. Design of artificial enzymes by site directed mutagenesis and chemical engineering of a protein cavity. Ph.D., University of Minnesota, Minneapolis, 2003.

Qi, D. Rational design of artificial transaminases by chemical and genetic approaches. Ph.D., University of Minnesota, Minneapolis, 2003.

Jalas, J. R. Stereo- and regioselectivity in the cytochrome P450-mediated metabolism of the tobacco-specific nitrosamine 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Ph.D., University of Minnesota, Minneapolis, 2003.

Rose, M. W. Attachment of azide containing isoprenoids onto a pentapeptide: a method for specifically labeling proteins via a modified staudinger ligation. M.S., University of Minnesota, Minneapolis, 2002.

Hsieh, S.-A. J. Studies directed towards the determination of the kinetic isotope effect of protein farnesyl transferase using mass spectrometry. M.S., University of Minnesota, Minneapolis, 2002.

Kuang, H. Rational design of protein-based catalysts. Ph.D., University of Minnesota, Minneapolis, 2001.

Kale, T. A. Photoactivatble prenylated cysteine analogs: synthesis and applications in studies of prenylated proteins. Ph.D., University of Minnesota, Minneapolis, 2001.

Weller, V. A. The enzymology of protein prenyltransferases: investigation of mechanism and inhibition. Ph.D., University of Minnesota, Minneapolis, 1999.

Turek, T. C. Enzymology of protein prenyltransferases: structural studies using photoaffinity labeling. Ph.D., University of Minnesota, Minneapolis, 1999.

Edelstein, R. L. Enzymatic protein prenylation: photoaffinity labeling and mechanistic studies of protein prenyltransferases. Ph.D., University of Minnesota, Minneapolis, 1997.

Davies, R. R. The stereoselective hydrolysis of amino acid esters by protein-catalyst conjugates. Ph.D., University of Minnesota, Minneapolis, 1997.

Pfaff, J. L. Understanding the role of phytoplankton lipids in bioaccumulation. Ph.D., University of Minnesota, Minneapolis, 1996.

Singh, S. K. Purification and preliminary characterization of yeast ras farnesyl transferase. B.S. Summa Cum Laude, University of Minnesota, Minneapolis, 1995.