CONTACT INFORMATION
Department of Chemistry
University of Minnesota
Minneapolis , MN 55455
Email: xiaoping@chem.umn.edu
Phone: 517-290-6356 (mobile)
612-624-5870 (lab)
PROFESSIONAL OBJECTIVES
To seek a challenging research, process development, quality assurance position in the area of separation science where my talents and skills can be fully utilized
HIGHLIGHTS
· Strong background in modern separation science, especially HPLC
· Broad background and hands-on experience in chiral separation
· Broad background and hands-on experience in multi-dimensional HPLC
· Extensive experience in HPLC method development, column packing and stationary phase characterization
· Extensive experience in laser-induced fluorescence detection and UV-vis detection
· Experience with GC, GC/MS, FTIR and AA technique
· Highly motivated and well organized, ability to handle multiple projects
· Excellent oral presentation and scientific writing skills
EDUCATION
Postdoc fellow, in University of Minnesota, Minneapolis, MN
Advisor: Peter W. Carr 2006 - present
Ph.D. in Analytical Chemistry, Michigan State University, East Lansing, MI
Advisor: Victoria L. McGuffin 2001 - 2006
B.S. in Chemistry, Nankai University, Tianjin, China
Advisor: Jiben Meng 2001
PROFESSIONAL EXPERIENCE
Postdoc fellow, Department of Chemistry, University of Minnesota (2006-present)
Ultra-fast two dimensional separations with liquid chromatography
· Effect of second dimensional gradient time is investigated.
· Comparison of two dimensional HPLC and NMR is investigated.
Graduate Research Assistant, Department of Chemistry, Michigan State University (2001-2006)
Chiral separations by liquid chromatography
· Effects of temperature and pressure to chiral separations with cyclodextrin stationary phase are investigated. (thermodynamic and kinetic characterizations)
· Effect of mobile phase composition to chiral separation with cyclodextrin stationary phase is investigated. (equilibrium achievement, nonlinear isotherm, thermodynamic and kinetic characterizations)
Stochastic simulation
· Theoretical methods for extracting kinetic rate constants in liquid chromatography are compared and evaluated. Peak tailing phenomenon is investigated.
Nitrogen-containing polycyclic aromatic hydrocarbons (N-PAH) characterization
· Thermodynamic and kinetic characterization of N-PAHs with ODS stationary phase
· Selective fluorescence quenching of N-PAHs by aliphatic amines
Teaching Assistant, Department of Chemistry, Michigan State University (2001-present)
· Separation Science (advanced level)
· Instrumental Methods and Applications
Research Assistant, Department of Chemistry, Center of Photochemistry, Nankai University; 2001
· Synthesis and characterization of pharmaceutical intermediate
PUBLICATIONS
Stoll, D.R.; Li, X.; Wang, X.; Carr, P.W.; Porter, S.E.G.; Rutan, S.C. “High temperature, fast two-dimensional liquid chromatography”, manuscript submitted
Li, X.; McGuffin, V.L. "Effect of mobile phase composition on chiral separation with cyclodextrin stationary phase", manuscript submitted
Li, X.; Hupp A.M.; McGuffin, V.L. “The thermodynamic and kinetic basis of liquid chromatography”, Advances in Chromatography, 2007
Li, X.; McGuffin, V.L. "Theoretical evaluation of methods for extracting retention factors and kinetic rate constants in liquid chromatography", J. Chromatogr. A, submitted
McGuffin, V.L.; Howerton, S.B.; Li, X. "Thermodynamic and kinetic characterization of nitrogen-containing polycyclic aromatic hydrocarbons in reversed phase liquid chromatography", J. Chromatogr. A, 2005, 2073 (1-2), 63-73
Li, X.; McGuffin, V.L. "Selective fluorescence quenching of nitrogen-containing polycyclic aromatic hydrocarbons by aliphatic amines", Anal. Chim. Acta., 2004, 526 (2), 155-162
PRESENTATIONS
Li, X., McGuffin, V.L. "Thermodynamics and kinetics of chiral separation with cyclodextrin stationary phase ", 30 th International symposium on HPLC conference, San Francisco, CA, June 2006
Li, X., McGuffin, V.L. "Effect of mobile phase composition on chiral separation with cyclodextrin stationary phase ", 57th Pittsburgh conference, Orlando, FL, March 2006
Li, X., McGuffin, V.L. "Theretical evaluation of several methods for extracting kinetic rate constants in liquid chromatography", 56th Pittsburgh conference, Orlando, FL, March 2005
McGuffin, V.L., Newman C.D., Li, X. "Fundamental studies of chiral complexation in capillary electrophoresis and chromatography", 228th ACS national meeting, Philadelphia, PA, August 2004
McGuffin, V.L., Howerton S.B., Li, X. "Thermodynamic and kinetic characterization of nitrogen-containing polycyclic aromatic hydrocarbons in reversed phase liquid chromatography", 28 th International Symposium on HPLC conference, Philadelphia, PA, June 2004
PROFESSIONAL AFFILIATION
American Chemistry Society, 2003-present
ACADEMIC HONORS
HPLC 2006 travel grant award, 2006
Graduate school travel funding fellowship, 2006
Basic-Subject Scholarship of Nankai University, 2000
Second-Class Scholarship of Nankai University, 1999
Outstanding Student of Nankai University, 1999
Third-Class Scholarship of Nankai University, 1998
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