Chemical Biology, A Single Molecule Perspective Molecular Biophysics, Biotechnology, and Chemistry-Biology Interface Joint Training Grant Symposium May 30, 2002 / 8 AM - 5 PM Earle Brown Center St. Paul Campus

Organizing Committee Arriaga Edgar Bowser Michael Veglia Gianluigi York Darrin Contact Information Carol Makkyla Phone: 612-624-9033 fax 612-626-7541 email: makkyla@chem.umn.edu For workshop information contact: Michael Bowser (bowser@chemumn.edu) For banquet information contact: Darrin York (york@chem.umn.edu)

*Registration/Abstract Submission Deadline is May 23, 2002.* The ability to observe, manipulate, and do measurements on single molecules is opening new avenues to understad the fundamentals of life. This one day symposium will showcase some of the recent findings in this field. Join us to enjoy the multiple presentations, a poster session, and a banquet. The speakers will include: Professor Norman Dovichi, University of Washington, Seattle "Single Molecule Enzymology" (http://faculty.washington.edu/dovichi/) Dr. Julio Fernandez, Mayo Clinic, Rochester, MN "Protein Mechanics Studied with Single Molecule AFM Techniques" (http://www.mayo.edu/research/people/4/4442_fernandez/) Professor Shuming Nie, Indiana University, Bloomington "Probing Single Molecules in Single Living Cells" (http://www.indiana.edu/~dnadna/index.html) Professor Mark Williams, Northeastern University, Boston "DNA Binding Protein Kinetics and Thermodynamics from Single Molecule Stretching Measurements" (http://www.atsweb.neu.edu/mark/) Professor Dave Thomas, University of Minnesota, Twin Cities "Spectroscopic resolution of molecular structures in contracting muscle" (http://ddt.biochem.umn.edu/) Professor Edgar Arriaga, University of Minnesota, Twin Cities "How many cardiolipin molecules are there in one mitochondrion? (http://www.chem.umn.edu/groups/arriaga/) Professor Mike Bowser, University of Minnesota, Twin Cities TBA (http://www.chem.umn.edu/groups/bowser/)   General Schedule 8:00 -9:00 Continental Breakfast and registration 8:40 Welcome 8:45 - 11:30 Morning session 11:30 - 1:40 Lunch buffet and Poster Session 1:40 - 5:00 Afternoon session 4:55 Closing Remarks and "Best Poster Award"

This symposium is sponsored by the following NIH training grants: Molecular Biophysics, Biotechnology, and the Chemistry-Biology Interface.